Hello, I have version 18.10 of GhostBSD, how could I update only with the iso, without a pendrive. To version 22?

Yes, there was a big change somewhere from freebsd 11.0 - freebsd 13.0 This change could not be accomplished without a new installation of GhostBSD. There was NO PATH from the old to the new. After the "new" the system is on the "rolling release path". I cannot remember with which version of GhostBSD that happened. I hope someone else will chime in here with a more complete answer. Can search on word "upgrade" in the Telegram channel or search here on this BBS. I am thinking more about your statement update only with the "iso" Maybe there is a method to use refind to boot the ghostbsd22.iso file???

See what dates are on the present year 2018 version:

uname -a
ghostbsd-version


Run the application to update:
update-station

#Some 5 commands to understand your disk setup
gpart status
gpart show
gpart show -l

geom disk list
camcontrol devlist

#how much free space on your disks.
df -h